The disclosure provides a method and a device in a User Equipment (UE) and a base station for wireless communication. In one embodiment, the UE receives first information, the first information being used for determining that Q1 subband(s) is(are) reserved in a first time-domain resource, listens in a first time-domain sub-resource to determine Q2 subband(s) from Q3 subband(s), and transmits second information, the second information being used for indicating the Q2 subband(s) and any one of the Q3 subband(s) being orthogonal to any one of the Q1 subband(s) in frequency domain; wherein a first carrier comprises both the Q1 subband(s) and the Q3 subband(s); and the first time-domain sub-resource belongs to the first time-domain resource. The disclosure can improve efficiency of transmission and utilization of spectrum.