Described embodiments provide systems and methods performing header protection. A device can receive from a client, a request relating to a first resource, for a second resource. The device can determine, using an identifier for the session, whether an address of the first resource has been previously accessed by the client during the session. The device can verify, using an address of the second resource, whether the address of the second resource is mapped to the address of the first resource for the session between the client and the device. The device can determine whether to provide access to the second resource responsive to the address of the first resource being previously accessed by the client during the session and the address of the second resource being mapped to the address of the first resource for the session.