Invention Grant
- Patent Title: Antagonist antibodies against human immune checkpoint CEACAM1 (CD66a) and formulations, kits, and methods of use thereof
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Application No.: US17309738Application Date: 2019-12-20
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Publication No.: US11377494B2Publication Date: 2022-07-05
- Inventor: Xingxing Zang
- Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Applicant Address: US NY Bronx
- Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee Address: US NY Bronx
- Agency: Perkins Coie LLP
- International Application: PCT/US2019/068176 WO 20191220
- International Announcement: WO2020/132654 WO 20200625
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K47/68

Abstract:
Provided are isolated antibodies and antigen-binding fragments thereof that specifically bind CEACAM1, including the IgV domain of CEACAM1, as well as pharmaceutical formulations, kits, and methods of use thereof.
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