Invention Grant
- Patent Title: Use of bromodomain-containing protein 9 antagonists in combination with vitamin D receptor agonists in diabetes treatment
-
Application No.: US16737312Application Date: 2020-01-08
-
Publication No.: US11376264B2Publication Date: 2022-07-05
- Inventor: Ronald M. Evans , Michael Downes , Zong Wei , Annette Atkins , Ruth T. Yu
- Applicant: Salk Institute for Biological Studies
- Applicant Address: US CA La Jolla
- Assignee: Salk Institute for Biological Studies
- Current Assignee: Salk Institute for Biological Studies
- Current Assignee Address: US CA La Jolla
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K31/59
- IPC: A61K31/59 ; A61P3/10 ; A61K9/00 ; A61K31/427 ; A61K31/4365 ; A61K31/4439 ; A61K45/06
Abstract:
Methods are provided for reducing blood glucose, which utilize an agent that increases the biological activity of a vitamin D receptor (VDR) (e.g., a VDR agonist), in combination with an antagonist of bromodomain-containing protein 9 (BRD9). IN some examples, such methods treat type II diabetes.
Information query
