A liquid crystal cell, a method of driving a liquid crystal cell, and a liquid-crystal-based spectacle lens are provided. The liquid crystal cell includes: a ring-like electrode layer, a liquid crystal layer, and an opposite electrode layer. The second ring-like electrode region is concentric with the first ring-like electrode region and surrounds the first ring-like electrode region; the first ring-like electrode region is configured to drive corresponding liquid crystal molecules in the liquid crystal layer, so as to form a first Fresnel zone plate region in the liquid crystal cell; the second ring-like electrode region is configured to drive corresponding liquid crystal molecules in the liquid crystal layer, so as to form a second Fresnel zone plate region of the liquid crystal cell; an order of the second Fresnel zone plate region is smaller than an order of the first Fresnel zone plate region.