The present application provides a display panel and a manufacturing method thereof. The display panel includes a first substrate, a plurality of bonding pads, an insulating adhesive, a sealant, a blocking layer, a second substrate, and a chip on film (COF). The display panel of the present application effectively reduces an area of a non-display region of a display panel in the prior art by side-bonding the COF and realizes an ultra-narrow bezel display with a width of the non-display region being less than 1 mm. Meanwhile, through a configuration of the blocking layer, the conductive adhesive can be prevented from overflowing and causing short circuits between each of the plurality of bonding pads.