Embodiments of the present disclosure provide a method and a device for determining a gaze placement and a computer readable storage medium. The method comprises acquiring an ocular image of a subject; determining at least one gaze characteristic vector based on an ocular image; determining a gaze placement of the subject, according to a gaze estimation model and the at least one characteristic vector. The characteristic vector comprises at least one of: a first characteristic vector from a first reference speckle center to a pupil center, wherein the first reference speckle is formed by a first reference source in the ocular image; a second characteristic vector from the pupil center to a second reference speckle center, wherein the second reference speckle is formed by a second reference source in the ocular image; a third characteristic vector from the second reference speckle center to the first reference speckle center.