Invention Grant
- Patent Title: Method for labeling of aldehyde containing target molecules
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Application No.: US16596539Application Date: 2019-10-08
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Publication No.: US11293060B2Publication Date: 2022-04-05
- Inventor: Frank Bergmann , Ian Quang Chau , Peter Crisalli , Hannah Marie Kallewaard-Lum , Hannes Kuchelmeister , Sebastian Johannes Pomplun , Hasham Saqib , Christian Wellner
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agent Pamela C. Ancona; Bryan Jones
- Priority: EP17166237 20170412
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6869 ; C07D295/13 ; C07D487/04 ; C07H21/02 ; C07H21/04 ; A61K47/68
Abstract:
The present invention relates to improving the processing rate of a sequencing reaction, for example in a nanopore sequencing reaction, by means of using improved nucleoside-tags. The tags are linked to the nucleoside phosphate via a Pictet Spengler reaction. Exemplary sequencing reactions that are improved by the present methods include nanopore-based nucleic acid sequencing-by-synthesis reactions.
Public/Granted literature
- US20200040392A1 METHOD FOR LABELING OF ALDEHYDE CONTAINING TARGET MOLECULES Public/Granted day:2020-02-06
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