- Patent Title: Polymer nanoparticle, polymer composition, method of making a polymer nanoparticle, method for treatment of bacterial biofilms, and method for detection of bacterial biofilms
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Application No.: US16321859Application Date: 2017-07-28
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Publication No.: US11291685B2Publication Date: 2022-04-05
- Inventor: Vincent M. Rotello , Ryan Francis Landis , Akash Gupta
- Applicant: THE UNIVERSITY OF MASSACHUSETTS
- Applicant Address: US MA Boston
- Assignee: THE UNIVERSITY OF MASSACHUSETTS
- Current Assignee: THE UNIVERSITY OF MASSACHUSETTS
- Current Assignee Address: US MA Boston
- Agency: Cantor Colburn LLP
- International Application: PCT/US2017/044312 WO 20170728
- International Announcement: WO2018/026643 WO 20180208
- Main IPC: A61K31/787
- IPC: A61K31/787 ; C08G61/12 ; C12Q1/04 ; A61K38/12 ; A01N43/36 ; A01N43/38 ; A01N43/90 ; A61K9/51 ; A61K45/06 ; C08G61/08 ; G01N33/569 ; A61K9/14

Abstract:
A polymer nanoparticle includes a polymer having repeating units of formula (I) wherein X, L1, and R1 are as defined herein. Methods of preparing the polymer nanoparticles and compositions comprising the nanoparticles are also disclosed. The polymers nanoparticles described herein are particularly useful for the treatment of bacterial biofilms.
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