A surgical stapling assembly is disclosed that comprises a retainer that is configured to be removably mounted to a staple cartridge that is configured to be operably seated in a stapling device. The retainer comprises an authentication key that is configured to defeat a first jaw lockout of the stapling device that is configured to prevent the jaws of the stapling device from closing. The stapling device further comprises a second lockout that is configured to prevent a firing member of the stapling device from advancing through a staple firing stroke when a spent staple cartridge is seated in one of the jaws.