Systems and methods for mitigating the impact of malware by reversing malware related modifications in a computing device are provided. According to an embodiment, a sandbox service running within a network security platform protecting an enterprise network receives a file containing malware and associated contextual information from an endpoint security solution running on an endpoint device, which has been infected by the malware. The sandbox service captures information regarding a first series of actions performed by the malware and based on the first series of actions generates a remediation script specifying a second series of actions that are configured to restore the endpoint device to a pre-infected state. The network security platform causes the endpoint device to be returned to the pre-infected state by causing the endpoint security solution to execute the remediation script on the endpoint device.