A display screen with an irregular shape is provided. The display screen with the irregular shape includes: an irregular-shaped display area including an irregular-shaped boundary and a pixel area, and the irregular-shaped boundary is located at a periphery of the pixel area; a packaging area provided at a periphery of the irregular-shaped boundary, the packaging is used to package the irregular-shaped display area; a number of connecting lines located between the irregular-shaped boundary and the packaging area, and the connecting lines are arranged along a direction from the irregular-shaped boundary to the packaging area. During arranging the connecting lines, along the direction from the irregular-shaped boundary to the packaging area, the connecting lines are bent, such that the plurality of connecting lines are compactly arranged. A display device is also provided.