Invention Grant
- Patent Title: CD47 antigen binding unit and uses thereof
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Application No.: US16481048Application Date: 2018-01-26
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Publication No.: US11267885B2Publication Date: 2022-03-08
- Inventor: Yangsheng Qiu , Jing Li , Honghai Gao , Fenglan Wu , Xu Fang , Shou Li , Hongtao Lu , James S. Yan , Lei Shi
- Applicant: ZLIP HOLDING LIMITED
- Applicant Address: KY Grand Cayman
- Assignee: ZLIP HOLDING LIMITED
- Current Assignee: ZLIP HOLDING LIMITED
- Current Assignee Address: KY Grand Cayman
- Agency: McDermott Will & Emery LLP
- Agent Judy M. Mohr; Brett A. Schweers
- Priority: WOPCT/CN2017/072738 20170126
- International Application: PCT/CN2018/074318 WO 20180126
- International Announcement: WO2018/137705 WO 20180802
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/00 ; C07K16/46 ; C07H21/04 ; C12P21/06 ; C12N5/02 ; C12N5/20 ; C07K16/28 ; A61P35/00

Abstract:
Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
Public/Granted literature
- US20200247886A1 CD47 ANTIGEN BINDING UNIT AND USES THEREOF Public/Granted day:2020-08-06
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