- Patent Title: Highly stable crystalline Eltrombopag monoethanolamine salt form D1
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Application No.: US17263642Application Date: 2019-07-25
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Publication No.: US11267791B2Publication Date: 2022-03-08
- Inventor: Nicolas Tesson , Jordi De Mier Vinue , Paolo Stabile , Pierluigi Padovan , Matteo De Poli , Angelo Restelli
- Applicant: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A.
- Applicant Address: IT Montecchio Maggiore
- Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A.
- Current Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A.
- Current Assignee Address: IT Montecchio Maggiore
- Agency: Lucas & Mercanti, LLP
- Priority: EP18187074 20180802
- International Application: PCT/EP2019/070077 WO 20190725
- International Announcement: WO2020/025449 WO 20200206
- Main IPC: C07D231/46
- IPC: C07D231/46
Abstract:
Object of the present invention is a highly stable crystalline form of Eltrombopag (ETP) monoethanolamine salt, named Form D1, having the highest thermodynamically stability with excellent non-hygroscopicity, and particularly well suitable for pharmaceutical purposes, with related process.
Public/Granted literature
- US20210284611A1 HIGHLY STABLE CRYSTALLINE ELTROMBOPAG MONOETHANOLAMINE SALT FORM D1 Public/Granted day:2021-09-16
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