- Patent Title: Chimeric antigen receptor (CAR) binding to BCMA, and uses thereof
-
Application No.: US16650580Application Date: 2019-01-31
-
Publication No.: US11266690B2Publication Date: 2022-03-08
- Inventor: Jianfeng Zhou , Junjian Liu , Guang Hu , Yongkun Yang , Guangrong Meng , Wenjing Gao , Yuyu Wang , Panpan Niu
- Applicant: NANJING IASO BIOTHERAPEUTICS CO., LTD. , INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
- Applicant Address: CN Jiangsu; CN Jiangsu
- Assignee: NANJING IASO BIOTHERAPEUTICS CO., LTD.,INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
- Current Assignee: NANJING IASO BIOTHERAPEUTICS CO., LTD.,INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
- Current Assignee Address: CN Jiangsu; CN Jiangsu
- Agency: Honigman LLP
- Agent Thomas A. Wootton, Esq.; Jonathan P. O'Brien
- Priority: CN201810100549.6 20180201,CN201811223693.5 20181019
- International Application: PCT/CN2019/074213 WO 20190131
- International Announcement: WO2019/149250 WO 20190808
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; A61K48/00 ; A61K35/17 ; A61P35/00 ; C07K14/725 ; C07K16/28 ; C12N15/62 ; C12N15/86 ; A01K67/00
Abstract:
The invention provides a chimeric antigen receptor (CAR) which can specifically bind to a BCMA protein comprising a BCMA binding structural domain, a transmembrane domain, a costimulatory domain, and an intracellular signaling domain. The invention also provides uses of the CAR in treating diseases or conditions linked to the expression of BCMA.
Public/Granted literature
- US20200246381A1 CHIMERIC ANTIGEN RECEPTOR (CAR) BINDING TO BCMA, AND USES THEREOF Public/Granted day:2020-08-06
Information query
