Invention Grant
- Patent Title: Choline salt forms of an HIV capsid inhibitor
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Application No.: US16892377Application Date: 2020-06-04
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Publication No.: US11266638B2Publication Date: 2022-03-08
- Inventor: Travis Lee Houston , Bing Shi
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Fish & Richardson P.C.
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/454 ; A61P31/18 ; A61K45/06

Abstract:
The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N—((S-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3- (trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus.
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