Invention Grant
- Patent Title: Electrochemical measurement of electron beam-induced pH change during liquid cell electron microscopy
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Application No.: US16919707Application Date: 2020-07-02
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Publication No.: US11264199B2Publication Date: 2022-03-01
- Inventor: Taylor Woehl , Mei Wang
- Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK
- Applicant Address: US MD College Park
- Assignee: UNIVERSITY OF MARYLAND, COLLEGE PARK
- Current Assignee: UNIVERSITY OF MARYLAND, COLLEGE PARK
- Current Assignee Address: US MD College Park
- Agency: Quarles & Brady LLP
- Main IPC: H01J37/20
- IPC: H01J37/20 ; H01J37/28

Abstract:
A microfluidic cell system to measure proton concentration in a fluid sample. The microfluidic cell system includes: a first microchip and a second microchip dimensioned to permit electron beam scanning of a fluid sample; a first membrane attached to the first microchip; a second membrane attached to the second microchip, the first membrane and the second membrane being disposed adjacent to one another with a space for the fluid sample therebetween, and the first membrane and the second membrane including a region of the fluid sample in which an electron beam is scanned; a first electrode patterned onto the first membrane and positioned a first distance from the region; a second electrode patterned onto the first microchip and positioned a second distance from the region, the first distance being less than the second distance; and a potentiostat in communication with the first electrode and the second electrode.
Public/Granted literature
- US20210249219A1 ELECTROCHEMICAL MEASUREMENT OF ELECTRON BEAM-INDUCED PH CHANGE DURING LIQUID CELL ELECTRON MICROSCOPY Public/Granted day:2021-08-12
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