A system on a chip (SoC) for smoke detection includes power regulator circuits coupled to respective pins and analog sensor amplifier circuits that are each coupled to a respective pin of the pins coupled to the power regulator circuits. A first analog sensor amplifier circuit of the analog sensor amplifier circuits has a photoelectric amplifier circuit, a first LED driver and a second LED driver. The SoC also has a digital core that includes a digital logic circuit, register bits, and an MCU communication circuit. The MCU communication circuit is coupled to a data pin, the register bits are coupled to control or modify operation of the power regulator circuits and the analog sensor amplifier circuits, and the register bits are operable to be written to by an MCU.