Invention Grant
- Patent Title: GDF-15 as a diagnostic marker to predict the clinical outcome of a treatment with immune checkpoint blockers
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Application No.: US15765174Application Date: 2016-09-30
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Publication No.: US11262360B2Publication Date: 2022-03-01
- Inventor: Jörg Wischhusen , Markus Haake , Reinhard Dummer , Matthias Mehling
- Applicant: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
- Applicant Address: DE Würzburg
- Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
- Current Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
- Current Assignee Address: DE Würzburg
- Agency: Dechert LLP
- Agent Andrew T Wilkins; Victoria E. Pedanou
- Priority: GB1517527.6 20151002,GB1607800.8 20160429
- International Application: PCT/EP2016/073519 WO 20160930
- International Announcement: WO2017/055612 WO 20170406
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/574
Abstract:
The present invention relates to methods for predicting the probability of a treatment response of a human cancer patient to an immune checkpoint blocker treatment e.g. with anti PD-1, and to methods for predicting the probability of survival of a human cancer patient following an immune checkpoint blocker treatment, and to apparatuses and kits which can be used in these methods.
Public/Granted literature
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