A drain treatment system includes a supply interface, a drainage interface, a water distribution assembly, a pod housing, and a controller. The supply interface is configured to connect to a water supply, the drainage interface is configured to connect to a drain, and the distribution assembly is configured to receive water from the water supply via the supply interface. The pod housing is configured to retain at least one pod containing a drain treatment compound, and the controller is configured to control a transfer of the water from the water distribution assembly to the pod housing, wherein the water is configured to carry the drain treatment compound from the at least one pod to the drainage interface for delivery to the drain.