Invention Grant
- Patent Title: Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV
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Application No.: US15448420Application Date: 2017-03-02
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Publication No.: US11260130B2Publication Date: 2022-03-01
- Inventor: Christopher Loose , Will Mclean , Megan Harrison , Michael R. Jirousek
- Applicant: Frequency Therapeutics, Inc.
- Applicant Address: US MA Lexington
- Assignee: Frequency Therapeutics, Inc.
- Current Assignee: Frequency Therapeutics, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Cooley LLP
- Agent J. Dean Farmer; Xixi Sun
- Main IPC: A61K47/34
- IPC: A61K47/34 ; A61K31/5377 ; A61K9/00 ; A61K45/06 ; A61K31/19

Abstract:
The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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