Disclosed is a radiation protection barrier. The radiation protection barrier includes at least one plain panel, each including an elongate frame, and a protective sheet attached to the elongate frame. The radiation protection barrier also includes at least one interventional panel coupled to the at least one plain panel, each of the at least one interventional panel(s) including an elongate frame, a protective sheet movably arranged on the elongate frame, a pair of sterile gloves arranged at an intermediate portion of the protective sheet, and a window configured on the protective sheet under the pair of sterile gloves. The radiation protection barrier further includes a plurality of wheel arrangements coupled to the elongate frames of the at least one plain and interventional panels.