- Patent Title: Monoclonal antibody and a method of use for the treatment of lupus
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Application No.: US16343127Application Date: 2017-10-17
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Publication No.: US11242401B2Publication Date: 2022-02-08
- Inventor: Pradip Nair , Ravindra Belavinakodige Sadashivarao , Ramakrishnan Melarkode
- Applicant: Biocon Limited
- Applicant Address: IN Bangalore
- Assignee: Biocon Limited
- Current Assignee: Biocon Limited
- Current Assignee Address: IN Bangalore
- Agency: Cooley LLP
- Priority: IN201641036145 20161021
- International Application: PCT/IB2017/056428 WO 20171017
- International Announcement: WO2018/073734 WO 20180426
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; C07K16/18 ; A61P37/06 ; A61P37/04 ; A61K45/06 ; A61K39/00
Abstract:
The present invention relates to compositions and methods useful for the treatment of lupus using a humanized IgG1 anti-CD6 monoclonal antibody (T1h) that binds to the SRCR domain 1 (D1) of CD6 without blocking the interaction of CD6 with the CD6 ligand Activated Leukocyte Cell Adhesion Molecule (ALCAM).
Public/Granted literature
- US20190241670A1 A MONOCLONAL ANTIBODY AND A METHOD OF USE FOR THE TREATMENT OF LUPUS Public/Granted day:2019-08-08
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