Invention Grant
- Patent Title: Monoclonal antibodies and cocktails for treatment of Ebola infections
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Application No.: US16896980Application Date: 2020-06-09
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Publication No.: US11242378B2Publication Date: 2022-02-08
- Inventor: Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
- Applicant: MAPP BIOPHARMACEUTICAL, INC. , Albert Einstein College of Medicine , Adimab, LLC
- Applicant Address: US CA San Diego; US NY Bronx; US NH Lebanon
- Assignee: MAPP BIOPHARMACEUTICAL, INC.,Albert Einstein College of Medicine,Adimab, LLC
- Current Assignee: MAPP BIOPHARMACEUTICAL, INC.,Albert Einstein College of Medicine,Adimab, LLC
- Current Assignee Address: US CA San Diego; US NY Bronx; US NH Lebanon
- Agency: Optima Law Group, APC
- Agent Thomas E. Jurgensen
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61P31/14 ; A61K39/42 ; A61K39/00

Abstract:
Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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