Invention Grant
- Patent Title: Stabilized radio-labeled anti-CD45 immunoglobulin compositions
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Application No.: US16456614Application Date: 2019-06-28
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Publication No.: US11241512B2Publication Date: 2022-02-08
- Inventor: Kaushik Dave , Shubh Sharma
- Applicant: Actinium Pharmaceuticals, Inc.
- Applicant Address: US NY New York
- Assignee: Actinium Pharmaceuticals, Inc.
- Current Assignee: Actinium Pharmaceuticals, Inc.
- Current Assignee Address: US NY New York
- Agency: Dentons Cohen & Grigsby P.C.
- Main IPC: A61K51/10
- IPC: A61K51/10 ; A61K35/28 ; C07K16/28 ; C07K16/30 ; A61K39/395 ; A61K9/00 ; A61K47/22 ; A61K47/32 ; A61K47/42 ; A61K35/12 ; A61K39/00
Abstract:
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.
Public/Granted literature
- US20190321498A1 STABILIZED RADIO-LABELED ANTI-CD45 IMMUNOGLOBULIN COMPOSITIONS Public/Granted day:2019-10-24
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