Embodiments of present disclosure relates to a method and an interactive infomercial system for enabling interactive infomercials. In one embodiment, the system receives a request for U3I (unique infomercial identification information) associated with infomercial content. The system determines the availability of pregenerated U3I and generate remaining number of U3I based on determination of non-availability of the requested U3I. Further, the system updates the generated U3I with at least one redirect URL that is activated to enable the rendering of the infomercial content on a user device. The system may also generate personalized U3Is based on user data. Thus, the above disclosed system and method enables real-time interactive infomercials to the users such that the U3Is are generated and stored in advance when the system is available and updated with animation content on demand in less time and quick response time.