Certain aspects and feature provide a host hypervisor that includes and advertises a virtual machine function that directs the host hypervisor to execute the next job with real-time priorities. A processing device can execute an application in a nested virtual machine, where the application includes at least one code section that relies on or makes use of real-time prioritized resources of the processing device. The processing device recognizes a virtual machine function call in response to the application determining that a code section using real-time prioritized resources is to be executed. The virtual machine function serves as a command that directs a host hypervisor to execute the next job (the next section of code to be executed) with real-time priorities. The processing device executes the code section in a real-time thread in response to the virtual machine function being called.