Disclosed herein is a method of predicting engine knocking, which includes calculating initial pressure in cylinder based on operating data and pressure in intake manifold measured using manifold absolute pressure sensor, calculating pressure at spark timing in the cylinder by interpreting compression process as polytropic process based on the calculated initial pressure in the cylinder, calculating heat release rate for individual operating conditions based on the calculated pressure in the cylinder at spark timing, calculating pressure change in the cylinder based on the calculated heat release rate, calculating unburned gas temperature in adiabatic compression process based on the calculated pressure change in the cylinder, and determining whether knock occurs by calculating ignition delay based on the calculated unburned gas temperature and calculating unburned gas mass fraction at crank angle at the end of the ignition delay.