Methods, apparatus, systems and articles of manufacture are disclosed to manage display luminance, for the purpose of power efficiency, halo reduction, and flicker prevention. An example apparatus includes a backlight analyzer to determine a first baseline luminance level associated with a first segment of a backlight of a screen of a display device based on pixel data defining a frame of content to be displayed via the screen and to determine a second baseline luminance level associated with a second segment of the backlight different than the first segment based on the pixel data, a segment-pair ratio analyzer to determine a segment-pair luminance ratio between the first and second segments based on the first and second baseline luminance levels, and a luminance controller to adjust an amount of power provided to at least one of the first segment of the backlight or the second segment of the backlight when the segment-pair luminance ratio satisfies a threshold.