A method and a system of determining a relation between two or more entities in a text document is disclosed. In an embodiment, the method may include receiving training text data annotated with two or more entities, and creating one or more n-grams based on the training text data. The method may further include generating a Convolutional Neural Network (CNN) model using the one or more n-grams, and creating an entity vector using at least one of a word embedding and a numeric embedding based on the training text data. The method may further include generating a relation-entity model using the CNN model and the entity vector.