Invention Grant
- Patent Title: Method for biocatalytic production of terpene compounds
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Application No.: US15734887Application Date: 2019-07-10
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Publication No.: US11214775B2Publication Date: 2022-01-04
- Inventor: Michel Schalk , Letizia Rocci , Daniel Solis Escalante
- Applicant: FIRMENICH SA
- Applicant Address: CH Satigny
- Assignee: FIRMENICH SA
- Current Assignee: FIRMENICH SA
- Current Assignee Address: CH Satigny
- Agency: Armstrong Teasdale LLP
- Priority: EP18182783 20180710
- International Application: PCT/EP2019/068609 WO 20190710
- International Announcement: WO2020/011883 WO 20200116
- Main IPC: C12N9/16
- IPC: C12N9/16 ; C12N9/04 ; C12P7/04 ; C12P7/18 ; C12P17/04

Abstract:
Provided herein are biocatalytic methods of producing terpene compounds by applying a novel type of phosphatase enzyme. The method allows the fully biochemical synthesis of terpene compounds, like for example copalol and labdendiol, and derivatives thereof, which serve as valuable intermediates for the production of perfumery ingredients, such as, for example, ambrox. Also provided are novel fully biochemical multistep processes for the production of such compounds as well as novel phosphatase enzymes and mutants and variants derived therefrom.
Public/Granted literature
- US20210222138A1 METHOD FOR BIOCATALYTIC PRODUCTION OF TERPENE COMPOUNDS Public/Granted day:2021-07-22
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