Invention Grant
- Patent Title: Epitopes in the RNA recognition motif 1 (RRM1) of TDP-43 and misfolding-selective antibodies thereto
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Application No.: US16616832Application Date: 2018-05-30
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Publication No.: US11214613B2Publication Date: 2022-01-04
- Inventor: Steven S. Plotkin , Neil R. Cashman , Xubiao Peng
- Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
- Applicant Address: CA Vancouver
- Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
- Current Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
- Current Assignee Address: CA Vancouver
- Agency: Bereskin & Parr LLP
- Agent Carmela De Luca; Amy Dam
- International Application: PCT/CA2018/050634 WO 20180530
- International Announcement: WO2018/218352 WO 20181206
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K5/12 ; C07K14/47 ; G01N33/68

Abstract:
The disclosure pertains to conformational epitopes in TDP-43, antibodies thereto and methods of making and using immunogens and antibodies specific thereto.
Public/Granted literature
- US20200165327A1 EPITOPES IN THE RNA RECOGNITION MOTIF 1 (RRM1) OF TDP-43 AND MISFOLDING-SELECTIVE ANTIBODIES THERETO Public/Granted day:2020-05-28
Information query