Invention Grant
- Patent Title: Small molecule inhibitors of MYC and uses thereof
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Application No.: US16641130Application Date: 2018-08-23
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Publication No.: US11214567B2Publication Date: 2022-01-04
- Inventor: Nouri Neamati , Yi Jin , Jun Lin
- Applicant: The Regents of the University of Michigan , YUNNAN UNIVERSITY
- Applicant Address: US MI Ann Arbor; CN Yunnan
- Assignee: The Regents of the University of Michigan,YUNNAN UNIVERSITY
- Current Assignee: The Regents of the University of Michigan,YUNNAN UNIVERSITY
- Current Assignee Address: US MI Ann Arbor; CN Yunnan
- Agency: Casimir Jones, S.C.
- Agent Robert A. Goetz
- International Application: PCT/US2018/047711 WO 20180823
- International Announcement: WO2019/040724 WO 20190228
- Main IPC: C07D413/10
- IPC: C07D413/10 ; C07D413/14 ; A61K45/00
Abstract:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having an oxadiazole-oxadiazolone structure (e.g., oxadiazole-phenyl-oxadiazolone compounds, oxadiazole-pyridine-oxadiazolone compounds, oxadiazole-indole-oxadiazolone compounds, oxadiazole-quinoline-oxadiazolone compounds, oxadiazole-pyrrole-oxadiazolone compounds, and oxadiazole-vinyl-oxadiazolone compounds), and their use as therapeutics for the treatment of cancer and other diseases.
Public/Granted literature
- US20200172528A1 SMALL MOLECULE INHIBITORS OF MYC AND USES THEREOF Public/Granted day:2020-06-04
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