Invention Grant
- Patent Title: Methods for safe and effective thrombolysis using sequential administration of tissue plasminogen activator and mutant pro-urokinase
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Application No.: US15523900Application Date: 2015-11-03
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Publication No.: US11213574B2Publication Date: 2022-01-04
- Inventor: Victor Gurewich
- Applicant: Thrombolytic Science, LLC
- Applicant Address: US MA Cambridge
- Assignee: Thrombolytic Science, LLC
- Current Assignee: Thrombolytic Science, LLC
- Current Assignee Address: US MA Cambridge
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2015/058878 WO 20151103
- International Announcement: WO2016/073514 WO 20160512
- Main IPC: A61K38/49
- IPC: A61K38/49 ; A61K38/57 ; A61P9/10 ; A61K9/00
Abstract:
Provided herein are methods for safe and effective thrombolysis in therapy for human subjects with symptoms of a potential stroke or acute myocardial infarction (“AMI”) using a sequential administration of a low dose bolus of human tissue plasminogen activator (“tPA”) followed by an infusion of a mutant form of human pro-urokinase (“proUK”).
Public/Granted literature
- US20180311322A1 METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE THROMBOLYSIS Public/Granted day:2018-11-01
Information query
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