A spine plate implant utilizes cam lock setscrews to retain bone screws in the plate once implanted. A cam lock setscrew is received in a setscrew pocket adjacent a configured bone screw bore of the plate and is configured to allow a bone screw to be received in the plate when in an unlocked rotational position, and to retain the received bone screw when in a locked rotational position. The bone screw may include a tang that allows engagement with external teeth of the cam lock setscrew when the cam lock setscrew is rotated into the locked position. Once the cam lock setscrew is in the locked position, the bone screw is inhibited from backing out of the bone screw bore. When the cam lock setscrew is in the unlocked position, a flat of the cam lock setscrew is adjacent the bone screw tang so the bone screw may be removed.