A driving circuit device for anti-leakage LED tube with dual-end input is provided. Two ends of the LED tube have two conductive pin assemblies electrically connected to mains supply. Each of the conductive pin assemblies includes two pins. One of the conductive pin assemblies is connected to an input bridge rectifier and has an output end. A constant current module has an input end. The input end of the constant current module is connected to the output end of the anti-leakage detection module. The anti-leakage detection module is provided for detecting a current state. A current is controlled to be outputted from the output end and to be inputted into the input end according to the current state, and the constant current module is changed to output a loop current not exceeding a rated standard.