The present disclosure relates power control in wireless communications, to methods for open loop power control for setting the initial uplink transmission power for a wireless device capable of operating in multiple frequency bands. The disclosure includes methods for transmitting an uplink signal in an uplink channel of a first frequency band using an initial transmission power based on measurements of reference signals in the first frequency band when the received downlink channel is in a second frequency band not overlapping with the first frequency band. The disclosure also relates to corresponding devices and to a computer program for executing the proposed methods. Further, embodiments relating to a host computer and activities therein, are also provided.