Systems and methods for using radio frequency signals and sensors to monitor environments (e.g., indoor building, industrial environments) are disclosed herein. In one embodiment, a system for providing a wireless asymmetric network comprises a hub having one or more processing units and at least one antenna for transmitting and receiving radio frequency (RF) communications in the wireless asymmetric network and a plurality of sensor nodes each having a wireless device with a transmitter and a receiver to enable bi-directional RF communications with the hub in the wireless asymmetric network. The one or more processing units of the hub are configured to determine localization of the plurality of sensor nodes within the wireless asymmetric network, to monitor regions within an environment for human presence and location of at least one robot, to determine human presence information to indicate whether a human is present within the monitored regions, and to determine a location for the human based on the human presence information when a human is present within the monitored regions.