Invention Grant
- Patent Title: Compositions and methods for detecting anti-endothelial cell antibodies in allograft rejection
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Application No.: US15512223Application Date: 2015-09-18
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Publication No.: US11029317B2Publication Date: 2021-06-08
- Inventor: Minnie M. Sarwal , Tara Sigdel , Annette M. Jackson
- Applicant: IMMUCOR GTI DIAGNOSTICS, INC. , THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US GA Norcross; US MD Baltimore
- Assignee: IMMUCOR GTI DIAGNOSTICS, INC.,THE JOHNS HOPKINS UNIVERSITY
- Current Assignee: IMMUCOR GTI DIAGNOSTICS, INC.,THE JOHNS HOPKINS UNIVERSITY
- Current Assignee Address: US GA Norcross; US MD Baltimore
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- International Application: PCT/US2015/050924 WO 20150918
- International Announcement: WO2016/044714 WO 20160324
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/50 ; G01N33/564
Abstract:
Provided herein are methods, compositions, and kits for diagnosing allograft rejection of organ transplants by identifying the presence of anti-endothelial cell antibodies. Such methods and compositions are independent of external confounders such as recipient age, transplant center, assay, cause of end-stage disease, co-morbidities, immunosuppression usage, and the like.
Public/Granted literature
- US20170276687A1 COMPOSITIONS AND METHODS FOR DETECTING ANTI-ENDOTHELIAL CELL ANTIBODIES IN ALLOGRAFT REJECTION Public/Granted day:2017-09-28
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