Invention Grant
- Patent Title: siRNA compositions that specifically down regulate expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease
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Application No.: US16735034Application Date: 2020-01-06
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Publication No.: US11028393B2Publication Date: 2021-06-08
- Inventor: Wanqing Liu , Yoon Yeo
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Brown Rudnick LLP
- Agent Adam M. Schoen
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61K31/713 ; A61K31/7088 ; A61K47/59 ; A61K47/58 ; A61K47/54 ; A61K47/69

Abstract:
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD).
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Information query
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