Invention Grant
- Patent Title: Methods of using 1-O-acetylbritannilatone spiro aryl isoxazoline compounds
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Application No.: US16805772Application Date: 2020-02-29
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Publication No.: US11028102B2Publication Date: 2021-06-08
- Inventor: Yonghong Tang , Minghui Chang , Huafeng Qi , Chengyuan Liang , Xingke Ju , Lei Tian , Yuzhi Liu , Han Li
- Applicant: XI'AN TAIKOMED PHARMACEUTICAL TECHNOLOGY CO., LTD.
- Applicant Address: CN Xi'an
- Assignee: XI'AN TAIKOMED PHARMACEUTICAL TECHNOLOGY CO., LTD.
- Current Assignee: XI'AN TAIKOMED PHARMACEUTICAL TECHNOLOGY CO., LTD.
- Current Assignee Address: CN Xi'an
- Priority: CN201711346227.1 20171215
- Main IPC: C07D498/10
- IPC: C07D498/10 ; A61P11/06 ; A61P29/00 ; C07D495/04
Abstract:
A method of inhibiting leukotriene include: administrating a therapeutically effective amount of a compound of chemical formula I or II or a pharmaceutical acceptable salt thereof to a subject, R1 is OH or OAc; X is C or N; and R2 is H, alkyl, alkoxy, benzyloxy, haloalkyl, OH, CN, NO2, or halogen, provided that when X is N, R2 is nil.
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