The present disclosure discloses system and method for facilitating avoiding of human errors in human error detection environment. At first, a plurality of configurations corresponding to a plurality of machines may be received. Further, a plurality of scripts may be configured corresponding to the plurality of machines based on the plurality of configurations. Further, a script, of the plurality of scripts, may be executed on a machine, of the plurality of machines. Based on the executing of the script, a message and a graphical user interface (GUI) may be displayed on the machines. Further, the message and the GUI may be customized based on the configuration of the machine. Further, the customized message and the GUI guide the user interacting with the machine to avoid the human errors.