A method, a device and a system for audio data communication are provided in the present invention. The method comprises: encoding audio data at a fixed interval to obtain a plurality of frames of encoded audio data; broadcasting M frames of the encoded audio data on a broadcast anchor time slot of a first time slot at a predetermined broadcast interval; and playing the audio data after delaying a predetermined time from an anchor of the first broadcast anchor slot. The predetermined time is configured for synchronous playback of the audio data at a local end and one or more opposite ends, the predetermined broadcast interval is M times of the fixed interval, M is a positive integer, the predetermined time is X times of the broadcast interval, and the X is a positive integer. Thereby, synchronous playback of audio data from one point to multiple points can be realized.