Invention Grant
- Patent Title: Substituted benzodiazoliums as ENaC inhibitors
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Application No.: US16462794Application Date: 2017-11-22
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Publication No.: US10941149B2Publication Date: 2021-03-09
- Inventor: Clive McCarthy , Jonathan David Hargrave , Duncan Alexander Hay , Thomas Beauregard Schofield , Naomi Went
- Applicant: ENTERPRISE THERAPEUTICS LIMITED
- Applicant Address: GB Brighton
- Assignee: ENTERPRISE THERAPEUTICS LIMITED
- Current Assignee: ENTERPRISE THERAPEUTICS LIMITED
- Current Assignee Address: GB Brighton
- Agency: Bookoff McAndrews, PLLC
- Priority: GB1619694 20161122
- International Application: PCT/GB2017/053499 WO 20171122
- International Announcement: WO2018/096325 WO 20180531
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04 ; A61P11/12 ; A61K9/00 ; A61K45/06
Abstract:
Compounds of general formula (I) wherein R1, R2, R3, R4, R5 and X are as defined herein are inhibitors of the epithelial sodium channel (ENaC) and are useful for the treatment or prevention respiratory diseases and conditions, skin conditions and ocular conditions.
Public/Granted literature
- US20190315757A1 BENZODIAZOLIUM COMPOUNDS AS ENaC INHIBITORS Public/Granted day:2019-10-17
Information query
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