Invention Grant
- Patent Title: DOTA synthesis
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Application No.: US16062205Application Date: 2016-12-19
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Publication No.: US10941124B2Publication Date: 2021-03-09
- Inventor: Andreas Richard Meijer , Arne Wang Aabye , Khalid Hussain , Sondre Nilsen , Mikkel Jacob Thaning , Jarle Andre Haugan , Ingvil Gausemel , Nikolai Enes , Silalahi Sumihar
- Applicant: GE Healthcare AS
- Applicant Address: NO Oslo
- Assignee: GE Healthcare AS
- Current Assignee: GE Healthcare AS
- Current Assignee Address: NO Oslo
- Agency: Culhane Meadows, PLLC
- Agent Jeff B. Vockrodt
- Priority: GB1522412 20151218
- International Application: PCT/EP2016/081705 WO 20161219
- International Announcement: WO2017/103258 WO 20170622
- Main IPC: C07D257/02
- IPC: C07D257/02 ; B01D9/00

Abstract:
The present invention provides methods for the preparation of compounds useful in in vivo therapeutic and diagnostic applications. In particular, the present invention provides a method for the synthesis of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and also methods for the preparation of metal chelates of DOTA.
Public/Granted literature
- US20180370925A1 DOTA SYNTHESIS Public/Granted day:2018-12-27
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