Invention Grant
- Patent Title: Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2
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Application No.: US14363724Application Date: 2012-12-07
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Publication No.: US10935548B2Publication Date: 2021-03-02
- Inventor: Joseph Anderberg , Jeff Gray , Paul McPherson , Kevin Nakamura , James Patrick Kampf
- Applicant: ASTUTE MEDICAL, INC.
- Applicant Address: US CA San Diego
- Assignee: ASTUTE MEDICAL, INC.
- Current Assignee: ASTUTE MEDICAL, INC.
- Current Assignee Address: US CA San Diego
- Agency: Womble Bond Dickinson (US) LLP
- International Application: PCT/US2012/068498 WO 20121207
- International Announcement: WO2013/086359 WO 20130613
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/545 ; G01N33/68
Abstract:
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in sepsis patients. In particular, the invention relates to using assays that detect one or more biomarkers selected from the group consisting of Insulin-like growth factor-binding protein 7, Beta-2-glycoprotein 1, Metalloproteinase inhibitor 2, Alpha-1 Antitrypsin, Leukocyte elastase, Serum Amyloid P Component, C-X-C motif chemokine 6, Immunoglobulin A, Immunoglobulin G subclass I, C-C motif chemokine 24, Neutrophil collagenase, Cathepsin D, C-X-C motif chemokine 13, Involucrin, Interleukin-6 receptor subunit beta, Hepatocyte Growth Factor, CXCL-1, -2, -3, Immunoglobulin G subclass II, Metalloproteinase inhibitor 4, C-C motif chemokine 18, Matrilysin, C-X-C motif chemokine 11, and Antileukoproteinase as diagnostic and prognostic biomarker assays of renal injury in the sepsis patient.
Public/Granted literature
- US20140377777A1 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE Public/Granted day:2014-12-25
Information query
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