The present application provides a pixel compensation device, a pixel compensation method, a pixel driving device, a timing control module and a display apparatus. The pixel compensation device includes a luminance conversion unit, an emitting voltage calculation unit, an emitting voltage offset calculation unit and a data conversion unit. The data conversion unit is configured to read pre-stored emitting voltage offset compensation data for a driving transistor in a sub-pixel unit with respect to a gate-source voltage of the driving transistor and obtain corresponding first luminance compensation data based on the emitting voltage offset and the emitting voltage offset compensation data. The data conversion unit is further configured to generate source luminance data based on the luminance signal data and the first luminance compensation data and output the source luminance data to a source driving module.