Invention Grant
- Patent Title: Predicting productivity in early cell line development
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Application No.: US15525324Application Date: 2015-11-12
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Publication No.: US10913985B2Publication Date: 2021-02-09
- Inventor: Uro{hacek over (s)} Jamnikar , Marjanca Blas , Kristina Gruden
- Applicant: Lek Pharmaceuticals d.d.
- Applicant Address: SI Ljubljana
- Assignee: Lek Pharmaceuticals d.d.
- Current Assignee: Lek Pharmaceuticals d.d.
- Current Assignee Address: SI Ljubljana
- Agency: Luedeka Neely Group, P.C.
- Priority: EP14192810 20141112
- International Application: PCT/EP2015/076391 WO 20151112
- International Announcement: WO2016/075217 WO 20160519
- Main IPC: C12Q1/6888
- IPC: C12Q1/6888 ; C12N15/67 ; C07K16/00 ; C12N5/071 ; C12P21/00
Abstract:
The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Fkbp10, ZdhhC6, Myrip, Actc1, AC124993.19, Runx2, AC158560.4, PlekhB1, Rps6KA2, Sept1, Sprr2k, and Flt1.
Public/Granted literature
- US20170321288A1 Predicting Productivity In Early Cell Line Development Public/Granted day:2017-11-09
Information query
