Invention Grant
- Patent Title: Compositions of, and methods for, alpha-1 anti trypsin Fc fusion molecules
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Application No.: US16539685Application Date: 2019-08-13
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Publication No.: US10913790B2Publication Date: 2021-02-09
- Inventor: Leland Shapiro
- Applicant: The Regents of the University of Colorado, a body corporate
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Polsinelli PC
- Main IPC: C07K14/81
- IPC: C07K14/81 ; A61K39/00 ; A61K45/00 ; A61K47/00 ; A61K39/42 ; A61K39/395 ; A61K39/38 ; C07K1/00 ; C07K14/00 ; C07K17/00 ; A61K31/519 ; A61K45/06 ; A61K38/57 ; C07K14/47 ; C07K16/00

Abstract:
A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), Mycobacterium avium complex (MAC), and anthrax in particular. Thus, the invention relates to modulation of cellular activities, including macrophage activity, and the like. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease.
Public/Granted literature
- US20200079836A1 COMPOSITIONS OF, AND METHODS FOR, ALPHA-1 ANTI TRYPSIN Fc FUSION MOLECULES Public/Granted day:2020-03-12
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