A server with a master-slave architecture and a method of reading and writing information thereof provided by the present disclosure include a master node, a multi-path selector and at least two slave nodes. Each slave node is connected to the master node through the multi-selector. The slave node includes a slave-node BIOS and a slave-node memory. The slave-node BIOS is configured to record slave-node information in the slave-node memory. The master node includes a master-node BIOS, a master-node memory and a baseboard management controller. The master-node BIOS is configured to record master-node information in the master-node memory. The baseboard management controller is configured to access the master-node memory and decide to access the slave-node memory of one of the slave nodes through the multi-path selector.